Florida State owns a 17-6 series advantage.
This will be the 1st Post-Season Meeting between the two schools.
Largest Margin of Victory: 59-0, Florida State, 1953.
Louisville Largest Margin of Victory: 63-20, 2016.
All-Time Record: Louisville 550-495-17 (.526), Florida State 580-280-17 (.671)
National Championships: Louisville 0, Florida State 3
Heisman Trophies: Louisville 1, Florida State 3
Conference Championships: Louisville 9, Florida State 15
Bowl Games: Louisville 25, Florida State 48
All-Americans: Louisville 3, Florida State 45
NFL Draft Picks: Louisville 131, Florida State 277
NFL 1st Rounders: Louisville 16, Florida State 46
Weeks in the AP Poll: Louisville 151, Florida State 580
Weeks at AP #1: Louisville 0, Florida State 72
# of times Hosting College GameDay: Louisville 3, Florida State 12
# of times appearing on College GameDay: Louisville 5, Florida State 35
Series History: Florida State Leads 17-6
| Location | Louisville | Florida State | Line* | Attendance | |
| 2022 | Louisville | 31 | 35 | +2.5 | 46,459 |
| 2021 | Tallahassee | 31 | 23 | +1 | 50,961 |
| 2020 | Louisville | 48 | 16 | -5.5 | 11,465# |
| 2019 | Tallahassee | 24 | 35 | +6.5 | 46,530 |
| 2018 | Louisville | 24 | 28 | +5 | 52,798 |
| 2017 | Tallahassee | 31 | 28 | +6 | 72,674 |
| 2016 | Louisville | 63 (#10) | 20 (#2) | +1 | 55,632 |
| 2015 | Tallahassee | 21 | 41 (#8) | +6.5 | 71,225 |
| 2014 | Louisville | 31 (#25) | 42 (#2) | +3.5 | 55,414 |
| 2002 | Louisville | 26 OT | 20 (#4) | +14.5 | 38,109 |
| 2000 | Tallahassee | 0 | 31 (#2) | +33.5 | 80,741 |
| 1991 | Louisville | 15 | 40 (#1) | 34,270 | |
| 1987 | Tallahassee | 9 | 32 (#4) | 53,114 | |
| 1986 | Louisville | 18 | 54 | 22,822 | |
| 1983 | Tallahassee | 7 | 51 | 42,117 | |
| 1982 | Tallahassee | 14 | 49 (#9) | 51,233 | |
| 1981 | Tallahassee | 0 | 17 (#19) | 50,735 | |
| 1980 | Tallahassee | 0 | 52 (#10) | 52,263 | |
| 1979 | Louisville | 0 | 27 (#9) | 27,306 | |
| 1970 | Tallahassee | 7 | 9 | ||
| 1954 | Louisville | 6 | 47 | ||
| 1953 | Tallahassee | 0 | 59 | ||
| 1952 | Tallahassee | 41 | 14 |
*Line is based on Louisville #COVID
Television Ratings:
| Network | Audience | |
| 2022 | ESPN | 2.75M |
| 2021 | ESPN2 | 643K |
| 2020 | RSN | |
| 2019 | ESPN | 1.54M |
| 2018 | ESPN 2 | 1.057M |
| 2017 | ESPN | 2.580M |
| 2016 | ABC | 6.216M |
| 2015 | ESPN | 2.852M |
| 2014 | ESPN | 4.97M |
| 2002 | ESPN | |
| 2000 | ESPN2 | |
| 1991 | WDRB | |
| 1987 | WHAS | |
| 1986 | – | |
| 1983 | TBS | |
| 1982 | TBS | |
| 1981 | WHAS | |
| 1980 | – | |
| 1979 | – | |
| 1970 | – |
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