| 2022 | Name | Ht | Wt | Post | Class | Changes Note |
| 0 | Derrick Edwards | 5-10 | 177 | DB | Fr. | added 8 lbs |
| 0 | Tyler Hudson | 6-2 | 197 | WR | Jr. | added to roster |
| 1 | Momo Sanogo | 6-1 | 227 | LB | R-Sr. | added to roster, removed Jordan Watkins |
| 2 | Khalib Johnson | 6-2 | 210 | QB | Fr. | added to roster |
| 2 | Chandler Jones | 5-10 | 186 | DB | Sr. | |
| 3 | Malik Cunningham | 6-1 | 190 | QB | R-Sr. | -10 lbs |
| 3 | Quincy Riley | 6-0 | 181 | CB | Jr. | added to roster |
| 4 | Braden Smith | 5-10 | 192 | WR | Jr. | |
| 5 | Marshon Ford | 6-2 | 240 | TE | R-Jr. | changed # from 83 |
| 5 | Josh Minkins | 6-2 | 196 | DB | Soph | added 17 lbs, changed # from 25 |
| 6 | Evan Conley | 6-2 | 212 | QB | Jr. | -3 lbs |
| 6 | Yaya Diaby | 6-4 | 270 | DL | Sr. | added 15 lbs |
| 7 | Tiyon Evans | 5-11 | 210 | RB | Jr. | added to roster |
| 7 | Monty Montgomery | 5-11 | 220 | LB | Sr. | -5 lbs |
| 9 | Ashton Gillotte | 6-2 | 265 | DL | Soph | added 3 lbs |
| 9 | Ahmari Huggins-Bruce | 5-10 | 163 | WR | Soph | added 3 lbs |
| 10 | Benjamin Perry | 6-2 | 212 | LB | Soph | added 42 lbs, changed to LB |
| 10 | Dee Wiggins | 6-3 | 195 | WR | Jr. | added to roster |
| 11 | Josh Johnson | 5-11 | 187 | WR | Gr. | |
| 11 | Dorian Jones | 6-0 | 235 | LB | R-So | changed from #44, added 5 lbs |
| 12 | Devaughn Mortimer | 5-11 | 178 | WR | Fr. | added to roster |
| 12 | Jarvis Brownlee | 5-11 | 182 | CB | Soph | added to roster |
| 13 | Kei’Trel Clark | 5-10 | 180 | DB | Jr. | |
| 14 | Marvin Dallas | 6-1 | 190 | LB | Sr. | -5 lbs |
| 15 | Jalen Mitchell | 5-10 | 214 | RB | Soph | -7 lbs |
| 15 | Kameron Wilson | 6-2 | 228 | LB | Soph. | added 8 lbs |
| 17 | Jackson Hamilton | 6-0 | 219 | LB | R-Fr. | added 17 lbs |
| 17 | Nathan McElroy | 6-2 | 195 | QB | Soph | |
| 18 | Rance Conner | 5-10 | 186 | DB | Soph | added 8 lbs |
| 19 | Brock Domann | 6-2 | 227 | QB | Jr. | added 2 lbs, switched to #19 |
| 19 | Popeye Williams | 6-3 | 230 | OLB | Fr. | added to roster |
| 20 | Victoine Brown | 6-4 | 241 | DL | R-Fr. | added 11 lbs |
| 20 | Maurice Turner | 5-10 | 180 | RB | Fr. | added to roster |
| 21 | Nicario Harper | 6-1 | 205 | LB | Jr. | added to roster/removed Aidan Robbins |
| 22 | Yasir Abdullah | 6-1 | 235 | LB | Sr. | |
| 23 | KJ Cloyd | 6-2 | 221 | LB | Jr. | added 6 lbs |
| 23 | Trevion Cooley | 5-10 | 211 | RB | So | added 11 lbs |
| 24 | Jaylin Alderman | 6-1 | 226 | LB | So. | added 11 lbs |
| 25 | D’Angelo Hutchinson | 6-3 | 185 | DB | Fr. | added to roster |
| 25 | Jawhar Jordan | 5-10 | 180 | RB | R-So | -6 lbs |
| 26 | MJ Griffin | 6-1 | 210 | S | So | added to roster |
| 27 | Kenderick Duncan | 6-3 | 206 | DB | R-Sr. | -19 lbs |
| 28 | Trey Franklin | 5-10 | 180 | DB | Jr. | |
| 29 | ||||||
| 30 | Grant Goodman | 5-11 | 195 | RB | Fr. | added to roster |
| 30 | Shavrick Williams | 6-0 | 185 | S | Jr. | |
| 31 | Zach Edwards | 6-3 | 265 | DL | R-So | |
| 32 | Ryheem Craig | 6-3 | 220 | DL | R-Fr. | added 10 lbs |
| 32 | James Turner | 6-0 | 205 | K | Jr. | added 9 lbs |
| 33 | Antonio Watts | 6-2 | 185 | Fr. | added to roster | |
| 34 | TJ Quinn | 6-0 | 225 | LB | R-Fr. | added 3 lbs |
| 35 | Jeremiah Caldwell | 6-3 | 175 | S | Fr. | |
| 36 | Jatavian Churchill | 5-11 | 172 | WR | So | -12 lbs |
| 37 | Jaylen Williams | 6-1 | 190 | DB | So. | |
| 37 | Austin Holland | Fr. | added to roster | |||
| 38 | Drew Brenowitz | 5-10 | 210 | LB | Sr. | |
| 39 | Justin Brummett | 6-0 | 192 | LS | So | |
| 40 | Darius Jones | 5-11 | 180 | DB | R-Fr. | |
| 40 | Brock Travelstead | 6-1 | 203 | K | So. | -11 lbs |
| 41 | Isaac Martin | 6-1 | 251 | TE | R-Sr. | added 1 lb |
| 41 | Ramon Puryear | 6-3 | 268 | DL | R-Soph | added 13 lbs |
| 42 | Josh Lifson | 6-3 | 230 | TE | R-Fr. | |
| 42 | Allen Smith | 6-2 | 230 | LB | R-So | |
| 43 | Jack Reiger | 6-1 | 225 | LB | So | |
| 44 | Selah Brown | 6-2 | 250 | DT | Fr. | added to roster |
| 44 | Francis Sherman | 6-3 | 237 | TE | R-Soph | |
| 45 | Duane Martin | 6-2 | 255 | TE | Soph | added 8 lbs |
| 45 | Seth Pugh | 6-2 | 200 | DB | Soph | added 15 lbs |
| 46 | Darrian Bell | 6-0 | 222 | LB | Soph | added 2 lbs |
| 47 | William Parr | 6-3 | 225 | TE | Soph | -10 lbs |
| 48 | Dakarian Sanders | 5-10 | 175 | DB | Fr | added to rosrer |
| 49 | Mark Vassett | 6-4 | 220 | P | Soph | added 5 lbs |
| 50 | Yirayah LaNier | 6-2 | 245 | DL | Soph | |
| 51 | Austin Collins | 6-3 | 283 | OL | Soph | added 13 lbs |
| 54 | Caleb Banks | 6-7 | 303 | DL | R-Fr. | added 38 lbs |
| 55 | Caleb Chandler | 6-4 | 300 | OL | R-Sr. | -13 lbs |
| 56 | Renato Brown | 6-4 | 317 | OL | R-So | added 8 lbs |
| 58 | Charlie Ely | 6-2 | 215 | R-Fr. | ||
| 60 | Sam Secrest | 6-6 | 295 | OL | Fr. | |
| 61 | Bryan Hudson | 6-4 | 310 | OL | R-Jr. | |
| 63 | Max Cabana | 6-6 | 292 | OL | R-Jr. | added to roster |
| 65 | Izaiah Reed | 6-6 | 295 | OG | Fr | added to roster |
| 67 | Luke Kandra | 6-4 | 314 | OL | Soph | added 22 lbs |
| 68 | Michael Gonzalez | 6-4 | 305 | OL | Soph | added 14 lbs |
| 70 | Trevor Reid | 6-5 | 307 | OL | Sr. | added 22 lbs |
| 71 | Joshua Black | 6-2 | 294 | OL | R-Soph | |
| 72 | Emmanual Sowders | 6-4 | 272 | OL | Sr. | |
| 74 | Adonis Boone | 6-5 | 295 | OL | Sr. | -22 lbs |
| 75 | Aaron Gunn | 6-4 | 312 | OL | R-Fr. | added 7 lbs |
| 76 | Travis Taylor | 6-3 | 285 | OL | Soph | |
| 77 | Kobe Baynes | 6-4 | 293 | OL | Jr. | |
| 79 | Makhete Gueye | 6-7 | 270 | OT | Fr. | added to roster |
| 80 | Chris Bell | 6-2 | 220 | WR | Fr. | added to roster |
| 81 | Christian Henry | 6-1 | 185 | WR | R-Fr. | |
| 82 | Victor Mullen | 6-7 | 240 | TE | R-Fr. | |
| 83 | Chance Morrow | 6-6 | 200 | WR | Fr. | |
| 84 | Dez Melton | 6-3 | 240 | TE | R-So | |
| 85 | Nate Kurisky | 6-3 | 225 | TE | Fr. | |
| 85 | Bradley West | 5-9 | 175 | WR | R-Fr. | |
| 86 | Elijah Downing | 6-3 | 196 | WR | R-Fr. | |
| 87 | Christian Pedersen | 6-3 | 230 | TE | R-Fr. | |
| 88 | Jaelin Carter | 6-2 | 208 | WR | Sr. | -7 lbs |
| 89 | Gage Reale | TE | Fr. | |||
| 90 | Jermayne Lole | 6-3 | 324 | DL | Sr. | added to roster |
| 91 | Tawfiq Thomas | 6-4 | 325 | DL | Fr. | added to roster |
| 92 | Henry Bryant | 5-11 | 277 | DL | So. | added 2 lbs, changed from #8 |
| 93 | Jared Dawson | 6-1 | 275 | DL | R-Fr. | added 17 lbs |
| 93 | Brady Hodges | 6-1 | 198 | K | So | added 18 lbs |
| 95 | Mason Reiger | 6-4 | 254 | DL | So | added 4 lbs |
| 96 | RJ Sorensen | 6-3 | 250 | DL | R-Fr. | added 8 lbs |
| 98 | Nick Keller | K | Fr. | |||
| 99 | Dez Tell | 6-1 | 285 | DL | Soph | added 19 lbs |
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@UofLSheriff50. Louisville native, University of Louisville Business School Grad c/o 2004. Co-Founder of TheCrunchZone.com
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